You’ve seen it in television ads, read it in newspaper articles, maybe even heard it from your doctor: depression is caused by a chemical imbalance in the brain that medication can correct. According to the chemical imbalance theory, low levels of the brain chemical serotonin lead to depression and depression medication works by bringing serotonin levels back to normal. However, the truth is that researchers know very little about how antidepressants work. There is no test that can measure the amount of serotonin in the living brain – no way to even know what a low or normal level of serotonin is, let alone show that depression medication fixes these levels.
The therapeutic effects of antidepressants are believed to be related to their effects on neurotransmitters. Monoamine oxidase inhibitors (MAOIs) block the break-down of monoamine neurotransmitters (serotonin and norepinephrine) by inhibiting the enzymes which oxidize them, thus leaving higher levels still active in the brain (synaptic cleft).
Tricyclic antidepressants (TCAs) prevent the reuptake of various neurotransmitters, including serotonin, norepinephrine, and dopamine. Selective serotonin reuptake inhibitors (SSRIs) more specifically prevent the reuptake of serotonin (thereby increasing the level of active serotonin in synapses of the brain). Other novel antidepressants specifically affect serotonin and other neurotransmitters.
A theory centered on neurotransmitter effects appears to be incomplete, however. Neurotransmitter levels are altered as soon as the antidepressant chemicals build up in the bloodstream, but effects on mood appear to occur several days or weeks later.
Most antidepressants have a delayed onset of action and are usually taken over the course of weeks, months, or sometimes years. They are generally considered distinct from stimulants, and drugs used for an immediate euphoric effect only are not generally considered antidepressants. Despite the name, antidepressants are often used in the treatment of other conditions, including anxiety disorders, bipolar disorder, obsessive compulsive disorder, eating disorders, and chronic pain. Some have also become known as lifestyle drugs or "mood brighteners".
Medicines sometimes cause unwanted side effects. For example, when you first start your antidepressant you may feel tired, have trouble sleeping or feel sick to your stomach. The side effects usually go away after a short time. Tell your doctor if you have any side effects. You should also let your doctor know if you take any other medicines, vitamins or herbal supplements.
Anti-Depressants-Pharmacy.com is a trusted and reliable online pharmacy, providing brand name and generic prescription drugs at a tremendous savings to thousands of customers worldwide. Our online pharmacy offers prescription drugs made by world renowned International pharmaceutical manufactures such as Novartis, Cipla Abbot, Aventis, Bayer, Cipla, Dr. Reddy's, Merck, Lilly, GlaxoSmithKline and Ranbaxy. At our online pharmacy all products including Celexa, Effexor XR, Elavil, Fluoxetine, Lexapro, Paxil, Paxil CR, Prozac, Remeron, Wellbutrin, Wellbutrin SR, Zoloft are shipped in the manufactures' original package with the manufactures' original seal for your safety.
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What is the difference between a Generic and Name-Brand Drug?
A Name-Brand drug is marketed under a specific trade name by a pharmaceutical manufacturer. In most cases, Name-Brand drugs are still under patent protection, meaning the manufacturer is the sole source for the product but in many Countries around the world this is not the case and a generic alternative is readily available . A generic drug is made with the same active ingredients in the same dosage form as a brand name drug. The generic drug is therapeutically equivalent to the brand name drug but is sold under its chemical or "generic" name.
Are Generic Drugs as Effective as Name-Brand Drugs?
A generic drug contains the same active ingredients in the same dosage form as a brand name drug. The strength and purity of generic medications are strictly regulated. The FDA requires all generic manufacturers to demonstrate that a generic drug will have the same medical effect as its Name-Brand equivalent by measuring the rate and extent of drug absorption. The generic drug should treat your illness or condition with the same effectiveness and safety as its brand name equivalent. Generics have to meet the same rigorous requirements as Name-Brand drugs.
Are Generic Drugs as Safe as Name-Brand Drugs?
These generics have been used billions of times by millions of patients, demonstrating again that Name-Brand and generic name drug have the same effect in the body.
Are Generic Drugs Less Expensive than Name-Brand Drugs?
In most cases, YES. The cost of researching, developing and marketing a new drug- including the money spent advertising the product- are factored into the price of the branded drug. Generic manufacturers spend considerably less on development and promotion, and therefore can afford to sell their product for less money.
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